Complement Factor H (CFH) is a pivotal regulator of the complement system, integral to maintaining immune homeostasis and protecting host tissues from undue complement‐mediated damage. By inhibiting ...
RGC-32, or Response Gene to Complement 32, plays a pivotal role in mediating cellular responses following complement activation. Acting as a regulator of the cell cycle, RGC-32 is implicated in ...
Northwestern Medicine investigators have uncovered a missing link behind the harmful effects of autoantibodies linked to ...
Commit Biologics (“Commit”), a biotechnology company pioneering complement system activation and backed by €21.5 million in ...
Sepsis is globally recognized as a primary contributor to morbidity and mortality. The Sepsis 3.0 definition is captured as ...
Our immune systems function by employing two separate responses when in contact with disease. The first is the innate immune system, which aids in monitoring for infection throughout the body. Innate ...
These miniature immune system models -- known as human immune organoids -- mimic the real-life environment where immune cells learn to recognize and attack harmful invaders and respond to vaccines.
For years, patients with C3G and IC-MPGN had few options to stop the progression toward kidney failure. Now a new class of ...
The article, titled "Emerging roles of immune cell-derived neurotransmitters in immunity and disease," published on March 17, 2026, in Immunity ...
The authors do not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and have disclosed no relevant affiliations beyond their ...