In 2005, two landmark papers describing novel cycle-array sequencing methods ushered in a new era in genetics. Known at the time as next-generation sequencing (NGS), these methods are now more ...

The field of gene expression continues to grow and evolve. Commonly used technologies such as microarrays are packing higher densities in a smaller footprint, and qPCR is becoming more accurate and ...

Researchers developed STRIPE, a targeted long-read RNA sequencing tool that identifies disease-causing variants missed by ...

For years, two siblings with the distinctive facial features of Treacher Collins syndrome had no genetic explanation for ...

This study generated two million short DNA sequences, known as signature sequences or sequence tags, to identify and quantify both known and novel small RNA molecules. with the Breaking Science News ...

Hospital for Sick Children in Toronto researchers are reporting that targeted RNA sequencing can detect clinically actionable alterations in 87% of tumors and provide decisive findings where DNA-seq ...

While DNA microarrays are already widely used, adapting the technology to RNA microarrays has proved difficult due to the lower stability of RNA. In 2018, the University of Vienna demonstrated how ...

Samples are commonly stored in a way that degrades RNA. Scientists are devising new ways to overcome this obstacle for RNA sequencing. RNA is more subject to degradation than DNA, whether chemical, ...

(Nanowerk News) An international research team led by the University of Vienna has succeeded in developing a new version of RNA building blocks with higher chemical reactivity and photosensitivity.

In the early 1980s, David Gilmour, now an emeritus biochemistry and molecular biology professor at Pennsylvania State University, joined the laboratory of geneticist and biochemist John Lis as a ...