These filmmakers have spoken openly about bipolar disorder or major depressive disorder, stigma, and the role creativity can ...

Understanding what depression is – and what it is not – is often the first step toward relief.

Depression-related fatigue is caused by cellular "overworking" at rest and a failure to produce energy under stress.

Hyperarousal plays an important role in mental disorders. It influences the severity of insomnia, depression, anxiety, ...

Researchers found that the cells of young adults with depression overproduce energy while resting but struggle to respond to ...

Depression and seasonal affective disorder (SAD) share similar symptoms, but depression can occur at any time of the year, while SAD follows a recurring seasonal pattern. For a SAD diagnosis, a person ...

Imagine wading through severe depression for years, taking medication after medication, with no relief. Now, envision discovering that what you were facing was not major depression but bipolar ...

Diagnosing bipolar disorder can be difficult. While it is not hard to distinguish between its two characteristic phases—the high spirits of mania and the low spirits of depression—it is challenging to ...

Spravato (esketamine) is a nasal spray used for depression and was approved by the FDA in 2019. It is specifically for treatment-resistant depression, meaning depression symptoms that have not gotten ...

Cannabis use disorder has a bidirectional and clinically meaningful association with major depressive disorder, new research suggests.