Key modifications involved in HCC include lysine methylation and acetylation, regulated by KMTs/KDMs and HATs/HDACs, respectively, which influence chromatin accessibility and transcriptional activity.

A molecular model showing three of the main epigenetic modifications of DNA (orange) and histones (dark blue) [JUAN GAERTNER/Science Photo Library/Getty Images] Post-translational modifications (PTMs) ...

When chromatin mapping, ChIP can fall short, and not all CUT&RUN kits perform the same. EpiCypher’s CUTANA™ CUT&RUN kit uses a proven workflow to deliver reproducible, publication-ready data for ...

A new review highlights the pivotal role of LSD1 (lysine-specific demethylase 1) in regulating critical cellular processes and its implications for human diseases. This article sheds light on how post ...

These modifications increase chromatin accessibility, influencing growth, differentiation, and ion transport, with contrasting effects on normal and colorectal cancer cells. Study: Short-chain fatty ...

Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...