A schematic showing the cytosine base editing intermediate and the various outcomes that can occur when the UNG protein is active. You may have seen it in the news recently: a baby in Pennsylvania ...

Human cells that have been edited with the new retron-based gene editing technology. Orange dots mark successful gene edits. Green dots show a fluorescent protein tag on the surface of mitochondria.

You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized treatment that repaired his specific genetic mutation. The treatment was ...

Most gene-editing tools cut DNA wherever they’re pointed, with no way to tell a tumor cell from a healthy one. A study ...

It may sound unreal, but by just altering one gene could one day help many people to permanently lower their dangerously high cholesterol and blood fat levels. This is the biggest takeaway from the ...

C&EN’s award-winning podcast Inflection Point leans on our 100-year archive to trace headline topics in science today back to their disparate and surprising roots. In each episode, we explore three ...

CRISPR has taken the bioengineering world by storm since its first introduction. From treating sickle cell diseases to creating disease-resistant crops, the technology continues to boast success on ...

Gene editing technologies have been used to improve agricultural products for more than two decades. One of the earliest editing technologies was Transfer DNA, T-DNA, which is extracted from ...

In the five years since Italy-based Chiesi Group established its rare disease division in Boston, the unit has landed regulatory approvals worldwide for 10 therapies — all small molecules and ...