Hidden within our bones, marrow sustains life by producing billions of blood cells daily, from oxygen-carrying red cells to immune-boosting white cells. This vital function is often disrupted in ...

Human periportal assembloid, showcasing the three key cell types of the liver: portal fibroblasts (magenta), cholangiocytes (green), and hepatocyte nuclei (blue). All cell borders are delineated in ...

Typically, bone marrow research relies heavily on animal models and oversimplified cell cultures in the laboratory. Now, researchers from the Department of Biomedicine at the University of Basel and ...

Researchers have developed a human intestinal cell model that closely mimics the structure and function of the human gut, enabling more precise prediction of drug-induced gastrointestinal toxicity ...

Assembloids: A Versatile Platform for Human Tissue Modeling. This schematic illustrates the classification of assembloids based on four key assembly strategies—multi-region, multi-lineage, ...

To create a cervix-on-a-chip, the researchers added cells that line the cervical canal to one channel of a microfluidic device. To an adjacent channel, they introduced cervical fibroblasts that form ...

In April, the FDA announced an ambitious plan to phase out animal testing requirements for monoclonal antibodies and other therapies in an effort to improve drug safety and reduce R&D costs. The goal ...

A breakthrough for biomedical research promises new insight into immunotherapy development and disease modeling. Scientists at The University of Texas Health Science Center at San Antonio have created ...