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ICAM-1:从免疫监视到病理过程
ICAM-1属于免疫球蛋白超家族成员,表达于多种细胞。ICAM-1是一种细胞表面糖蛋白和粘附受体,以调节白细胞从循环到炎症部位的募集而闻名,参与细胞的信号转导与活化、免疫应答、炎症反应等重要生理过程。ICAM-1在肿瘤发生发展中具有重要作用,在多发性骨髓 ...
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