All animals possess some capacity for repairing and replacing the lining of their intestines, a process called intestinal regeneration. In mammals, including humans, this constant but relatively minor ...

All animals possess some capacity for repairing and replacing the lining of their intestines, a process called intestinal regeneration. In mammals, including humans, this constant but relatively minor ...

Two independent studies by Columbia scientists suggest that research into the gut’s stem cells over the past 15 years has been marred by a case of mistaken identity: Scientists have been studying the ...

Chemical and Biological Engineering PhD student Max Yavitt is the lead author on a new paper in Science Advancesthat focuses on intestinal tissue research. The work could allow researchers to control ...

As people live longer, the gut quietly accumulates damage that can tip the balance between healthy tissue renewal and chronic disease. Researchers have now traced a key part of that shift to specific ...

During drug development, researchers need to perform adequate nonclinical testing to ensure a drug’s safety and efficacy before starting clinical trials. An important aspect they must evaluate is a ...

Our intestine plays a vital role in absorbing nutrients and provides a protective barrier within the digestive tract. As a consequence of these functions, the epithelial cells lining the intestine are ...

The human small intestine is an essential organ that helps us absorb nutrients and vitamins from food. It is an average of 6 meters long and is covered with millions of villi that are separated by ...

Colorectal cancers, which kill more than 900,000 people each year, are notoriously heterogeneous. The cell type and the genetic mutations that give rise to the tumors and the effect of the tumor ...