A risky but often lifesaving surgery that removes damaged parts of the small intestine can leave patients facing a new threat: serious liver damage with no available treatment. Now, scientists have ...

“One day this technology will allow us to grow a section of healthy intestine for transplant into a patient,” said coauthor Michael Helmrath of Cincinnati Children's, in a press release. “But the ...

Under the surface of an organ, many different cell types participate in crucial interactions. This means that when an organ suffers damage, fixing it is not as easy as slapping on a Band-Aid.

While in vivo animal models are commonly employed for pharmacokinetic studies, they are often expensive, low in throughpu,t and typically fail to accurately replicate key characteristics of the human ...

For decades, lab-grown cells have been studied in materials that don't reflect the softness and flexibility of human tissue. Now researchers at the University of Colorado Boulder have developed a ...

Researchers at the University of Gothenburg, Sweden, have uncovered a critical mechanism that may pave the way for innovative treatments for Crohn's disease. Their findings center on repairing the ...

The terms "intestinal barrier" and "intestinal permeability" describe two different aspects of the same anatomical structure, the intestinal wall composed of four layers, the mucosa, the submucosa, ...

Researchers developed a compound that protects the liver after small bowel resection in mice. The drug improved nutrient absorption, reduced fibrosis, and avoided systemic side effects, offering hope ...

A recent study investigated whether a transglutaminase 2 inhibitor has potential as a drug to treat celiac disease. Previous tissue studies have shown that the ZED1227 transglutaminase 2 inhibitor ...