3月5日,国际顶级学术期刊《自然》(Nature)正刊在线发表重磅研究成果《Lipid metabolism drives dietary effects on T cell ferroptosis and immunity》(脂质代谢驱动饮食对T细胞铁死亡和免疫的影响)。 该研究由澳大利亚健康与医学科学院院士、昆士兰大学免疫学教授余迪团队领衔,湖北民族大学附属民大医院为第一作者单位,这是恩施州内 ...
引言俗话说“人如其食”,这句古老的谚语在现代生命科学的显微镜下,正在展现出令人震撼的分子生物学意义。我们每天摄入的营养物质,不仅仅是维持机体运转的能量燃料,更是直接参与细胞命运决策的信号分子。近年来,免疫学领域的一个核心议题是:机体的外在环境(尤其是饮食结构)究竟是如何跨越宏观的消化系统,在微观层面 ...
1869年创刊于英国伦敦的《自然》是全球最具影响力的多学科科学期刊之一。此次发表的成果,是民大医院与余迪团队长期深度科研合作的标志性产出,也是在前期发表于《自然-免疫学》的“硒—硒蛋白GPX4功能轴保护T细胞免于铁死亡机制”重要研究基础上的再次大突破。研究首次揭示了饮食中的多不饱和脂肪酸(PUFA)与单不饱和脂肪酸(MUFA)可直接重塑T细胞脂质组成,调控其铁死亡抗性,进而深刻影响T细胞稳态、分化 ...
In a recent study published in Nutrients, scientists provide a detailed overview on age-related alterations in lipid metabolism and its association with age-related chronic diseases. Study: The Roles ...
A schematic illustration of the role of DHHC5 and CRYBG1 in controlling lacteal function and intestinal lipid absorption by maintaining the lipid raft association of VEGFR2. The proper functioning of ...
(Monday 14 October 2024, Vienna, Austria) Researchers have unveiled a novel approach to tackle obesity by targeting fat absorption in the small intestine. The cutting-edge nanoparticle system, ...
Fatty liver disease is a growing global health concern. Proglucagon-derived peptides (PGDPs), including glucagon, GLP-1, and GLP-2, are known to regulate lipid metabolism in the liver. However, the ...
Scientists at UCLA described a previously unknown step in the complex process by which dietary cholesterol is processed in the intestines before being released into the bloodstream. The finding might ...
Hoth Therapeutics, Inc. (NASDAQ: HOTH), a clinical-stage biopharmaceutical company focused on developing innovative therapies for patients with unmet medical needs, today announced new female-specific ...
Trying to lower cholesterol? Dietitians say snacking at this common time of day may work against your heart-health goals.