New research reveals that subtle chemical changes to proteins after synthesis play a critical role in determining ...

Inside every human cell, proteins are constantly being tagged with small chemical modifications after they're produced. Known ...

As the “Method of the Year 2024”, spatial proteomics (SP) enables in situ characterization of protein localization, abundance, and interactions across subcellular to tissue scales, surpassing ...

Objectives Smoking is recognised as one of the strongest environmental risk factors for the development of rheumatoid ...

A molecular model showing three of the main epigenetic modifications of DNA (orange) and histones (dark blue) [JUAN GAERTNER/Science Photo Library/Getty Images] Post-translational modifications (PTMs) ...

Protein changes matter: Scripps Research showed that post-translational modifications can make proteins more or less responsive to drug-like molecules, affecting treatment success. Genetics meets ...

Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...