Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...

Gram-stained section of a macrophage with ingested S epidermidis bacteria, seen as purple granules within its cytoplasm. In this stain, the nucleus appears pale, with a reddish nucleolus. It is ...

Cancer incidence rises sharply with age, yet the biological mechanisms that make older patients more vulnerable to treatment failure remain poorly ...

A mature cell of one type can be turned into a mature cell of another type without the cell having to pass through an earlier stage of development. This is called direct reprogramming, a reliable but ...

Unlike transient innate immune activation, trained immunity is characterized by long-lasting but reversible functional reprogramming of monocytes, macrophages, natural killer (NK) cells, and ...