在经典群体遗传学理论中，重组被视为维持遗传多样性、提高选择效率的重要机制。然而，越来越多的基因组研究表明，植物基因组中的重组并非均匀发生。某些区域由于染色体倒位、转座子富集、染色质状态改变或着丝粒环境等因素，长期处于低重组状态。这些看似“沉默”的区域，并非进化的边缘地带，相反，它们往往成为适应性变异积累、基因组合锁定乃至物种分化的重要舞台。

RNA-Based Homologous Recombination Deficiency Signature Detects Homologous Recombination Deficiency-RNA+ Patients With and Without Homologous Recombination Repair Gene Pathogenic Alterations in Men ...

An analysis of millions of SARS-CoV-2 genomes finds that recombination of the virus is uncommon, but when it occurs, it is most often in the spike protein region, the area which allows the virus to ...

Scientists at deCODE genetics/Amgen have constructed a complete map of how human DNA is mixed as it is passed down during reproduction. The map marks a major step in the understanding of genetic ...

New findings suggest an explanation for the century-old mystery of how chromosome recombination is regulated during sexual reproduction. In most higher organisms, including humans, every cell carries ...

Use of an RNA-based HRD signature significantly expands the fraction of patients with prostate cancer who may derive benefit from poly (ADP-ribose) polymerase inhibitors (PARPis) compared with using ...

When the genomes of parents come together to create the genome of a child, their DNA recombines; similar parts are rearranged so that a child carries sections of their parents genomes that have been ...