Researchers have shown for the first time how Merkel cell polyomavirus (MCV), which causes an aggressive skin cancer called Merkel cell carcinoma, initiates DNA replication in host cells. University ...

The avian influenza virus needs to mutate to cross the species barrier and to infect and replicate within mammalian cells. Scientists have now deciphered the structure of the avian influenza virus's ...

The influenza virus continues to pose a threat to our health. It triggers seasonal epidemics and, from time to time, potentially serious global pandemics. Existing antiviral drugs are often less ...

Ongoing research aims to confirm the mechanism by which ICP4 fluidizes the nucleus, which could indicate specific targets to counter viral replication.

This story is part of a larger series on viroids and virusoids, small infectious RNAs. It is also the sixth installment in a series on hepatitis D virus, a virusoid-like pathogen that causes serious ...

The rate of HIV infection continues to climb globally. Around 40 million people live with HIV-1, the most common HIV strain. While symptoms can now be better managed with lifelong treatment, there is ...

Prevention remains critical; but once symptoms appear, treatment options are extremely limited. Because rabies hides behind a complex molecular shield, it is nearly impossible to fight. “For more than ...

Herpes simplex virus partially liquefies the tightly packed, gel-like interior of human cell nuclei to copy itself faster, a new study shows. The research centers on how the nucleus of each human cell ...

It starts quietly, a bite or a scratch, and by the time symptoms surface, it’s often too late. Rabies isn’t just a distant threat—it’s alive and present here in Alabama. Prevention remains critical, ...

On the left is integrase in its “intasome” structure of four identical four-part complexes (pink) that connect to create one 16-part complex that locks around viral DNA (blue). On the right is ...