In a recent study, led by corresponding author, Anna-Maria Liphardt, PhD, of the Rheumatology and Immunology Department at Friedrich-Alexander-Universität Erlangen-Nürnberg and the ...

Researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have discovered a specialized population of neutrophils in the skin that produce extracellular matrix components, helping ...

Amyotrophic lateral sclerosis and frontotemporal dementia are heterogeneous diseases that are difficult to fully model in mice. One of the more common forms is caused by hexanucleotide repeat ...

For in vitro cellular assays, the extracellular matrix—the material between cells—often is overlooked, but changes within this microenvironment affect cells’ proliferation and differentiation and, ...

Cartilage injuries are a common clinical issue, often caused by trauma, severe infections, or degenerative joint diseases. The lack of direct blood supply to cartilage and limited access to nutrients ...

Scientists are uncovering surprising complexity in connective tissues, from diverse fibroblast subtypes to collagen’s hidden fat molecules and the extracellular matrix’s role in disease. These ...